Description

6α-[[[4-(Acetylamino)Phenyl]Acetyl]Amino]Penicillanic Acid is a key semi-synthetic penicillin derivative and a crucial intermediate in the synthesis of advanced β-lactam antibiotics. This compound matters for its role in developing potent antimicrobial agents with targeted activity, offering pharmaceutical manufacturers a reliable building block for complex drug synthesis. It is primarily needed by research institutions and pharmaceutical companies engaged in the development and production of next-generation antibiotics and other therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel penicillin and cephalosporin-based antibiotics.
• Antimicrobial Research: Used in biochemical and pharmacological research to study structure-activity relationships (SAR) of β-lactam compounds.
• Active Pharmaceutical Ingredient (API) Development: A key starting material in the multi-step synthesis of complex antibiotic APIs.
• Process Chemistry: Employed in scale-up and optimization studies for the industrial manufacturing of specialized antibiotics.

Basic Information

Product Name	6α-[[[4-(Acetylamino)Phenyl]Acetyl]Amino]Penicillanic Acid
CAS No.	18555-08-3
Molecular Formula	C22H23N3O6S
Molecular Weight	457.50 g/mol
Synonyms	6-[[[4-(Acetylamino)Phenyl]Acetyl]Amino]penicillanic Acid; 6-APA Derivative; N-(4-Acetamidobenzoyl)-6-aminopenicillanic Acid; 6-[(4-Acetamidobenzamido)]penicillanic Acid; Ampicillin Intermediate; Penicillin G Amide Derivative; (2S,5R,6R)-6-[[(4-Acetamidophenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 6α-[[[4-(Acetylamino)Phenyl]Acetyl]Amino]Penicillanic Acid is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC and NMR, to ensure high purity and consistency suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.