Description

2,3-Difluorobenzoic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with tailored biological and physical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluoro moiety enhances bioavailability and stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies.
• Polymer Modification: Incorporated into polymer chains to alter thermal stability, chemical resistance, and surface properties of high-performance plastics.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for electron-transport materials and emissive layer components.
• Chemical Research & Development: A valuable reagent for exploring new fluorination reactions and structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	2,3-Difluorobenzoic Acid
CAS No.	18355-75-4
Molecular Formula	C7H4F2O2
Molecular Weight	158.10 g/mol
Synonyms	Benzoic acid, 2,3-difluoro-; 2,3-Difluorobenzenecarboxylic acid; 2,3-DFBA; 2,3-Difluoro-benzoic acid; 2,3-Difluorobenzoic acid, 98+%; 2,3-Difluorobenzoic acid, 99%
EINECS	Contact for details

Quality Control

Our 2,3-Difluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global customer base. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	155°C - 160°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.