Description

2-[3-(Trifluoromethyl)Benzoyl]Aminoacetic Acid is a high-purity, specialized organic intermediate featuring a benzoyl aminoacetic acid core substituted with a trifluoromethyl group. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceuticals and agrochemicals, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the CF3 group improves biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Peptidomimetic Research: Employed in medicinal chemistry for constructing peptide analogs and protease inhibitors due to its aminoacetic acid moiety.
• Material Science: Potential monomer or additive for synthesizing specialty polymers with unique surface properties or fluorinated coatings.
• Chemical Biology Probes: Used to create molecular probes for studying enzyme function and protein-protein interactions in biochemical research.

Basic Information

Product Name	2-[3-(Trifluoromethyl)Benzoyl]Aminoacetic Acid
CAS No.	17794-48-8
Molecular Formula	C10H8F3NO3
Molecular Weight	247.17 g/mol
Synonyms	N-[3-(Trifluoromethyl)benzoyl]glycine; 2-[[[3-(Trifluoromethyl)phenyl]carbonyl]amino]acetic acid; 3-Trifluoromethylhippuric Acid; m-Trifluoromethylhippuric Acid; Glycine, N-[3-(trifluoromethyl)benzoyl]-; Aminoacetic acid, N-[3-(trifluoromethyl)benzoyl]-; (3-Trifluoromethylbenzamido)acetic Acid
EINECS	Contact for details

Quality Control

Our 2-[3-(Trifluoromethyl)Benzoyl]Aminoacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.