Description

4-o-[2-(Dimethylamino)-2-Oxoethyl]Rifamycin is a key semi-synthetic derivative of the rifamycin class of antibiotics, primarily recognized for its role as a crucial intermediate in pharmaceutical synthesis. This compound matters for its specific structural modifications that enable the development of advanced antibacterial agents with targeted activity. It is essential for manufacturers and research institutions in the pharmaceutical industry focused on developing next-generation antibiotics to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of advanced rifamycin-based antibiotics.
• Antibacterial Drug Development: Serves as a precursor for research and production of drugs targeting gram-positive bacteria and tuberculosis.
• Biochemical Research: Used in studies investigating bacterial RNA polymerase inhibition and mechanisms of antibiotic action.
• Veterinary Medicine: Potential application in developing antibacterial treatments for animal health.
• Reference Standard: Employed as a high-purity standard in analytical laboratories for quality control and method development.

Basic Information

Product Name	4-o-[2-(Dimethylamino)-2-Oxoethyl]Rifamycin
CAS No.	17607-33-9
Molecular Formula	C39H50N2O13
Molecular Weight	754.82 g/mol
Synonyms	4-O-[2-(Dimethylamino)-2-oxoethyl]rifamycin; Rifamycin 4-O-[2-(dimethylamino)-2-oxoethyl] derivative; 4-Deoxy-4'-O-[2-(dimethylamino)-2-oxoethyl]rifamycin SV; (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-21-Acetoxy-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-8-yl 2-(dimethylamino)-2-oxoacetate
EINECS	Contact for details

Quality Control

Our 4-o-[2-(Dimethylamino)-2-Oxoethyl]Rifamycin is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) documenting full specifications are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and potency.

Specification

Item	Specification
Appearance	Orange to reddish-brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.