Description

25-Deacetoxy-25-Hydroxyrifamycin S is a key semi-synthetic intermediate derived from the rifamycin family of antibiotics. This compound is of significant value in pharmaceutical research and development, particularly for the synthesis of novel rifamycin derivatives with potential therapeutic applications. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in antibiotic discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of advanced rifamycin analogs and next-generation antibiotics.
• Antibacterial Research: Used in biochemical and microbiological studies to investigate structure-activity relationships (SAR) against bacterial targets.
• Process Development: Serves as a reference standard and starting material in the scale-up and optimization of antibiotic manufacturing processes.
• Academic Research: Employed in university and institutional labs for studying the biosynthesis and chemical modification of ansamycin antibiotics.

Basic Information

Product Name	25-Deacetoxy-25-Hydroxyrifamycin S
CAS No.	17555-51-0
Molecular Formula	C38H47NO13
Molecular Weight	725.78 g/mol
Synonyms	25-Deacetoxy-25-hydroxy-rifamycin S; Rifamycin S, 25-deacetoxy-25-hydroxy-; 25-Deacetoxy-25-hydroxy-rifamycin S; 25-Hydroxy-25-deacetoxy-rifamycin S; 25-Deacetoxy-25-hydroxyrifamycin S; (12Z,14E,24E)-(2S,12S,13S,14R,15S,16S,17R,18R,19S,20R,21S,22R,23S)-21-Acetyloxy-6,9,17,19-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-5-yl acetate
EINECS	Contact for details

Quality Control

Our 25-Deacetoxy-25-Hydroxyrifamycin S is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Reddish-brown to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0%
Related Substances (HPLC)	Total impurities ≤5.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.