Description

4-o-[2-(Methylpropylamino)-2-Oxoethyl]Rifamycin is a semi-synthetic derivative of the rifamycin class of antibiotics, known for its potent antibacterial activity. This compound is a key intermediate in the synthesis of advanced antimicrobial agents, offering significant value in pharmaceutical research and development. It is primarily sought by manufacturers and research institutions in the pharmaceutical and biotechnology sectors for developing novel therapeutic formulations targeting resistant bacterial strains.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of next-generation rifamycin-based antibiotics.
• Antimicrobial Research: Used in R&D for studying structure-activity relationships and developing new antibacterial agents.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the manufacturing process of finished dosage forms.
• Biochemical Studies: Employed in microbiological and pharmacological research to investigate mechanisms of action against bacteria.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical production.

Basic Information

Product Name	4-o-[2-(Methylpropylamino)-2-Oxoethyl]Rifamycin
CAS No.	16784-10-4
Molecular Formula	C38H49N3O12
Molecular Weight	739.81 g/mol
Synonyms	Rifamycin Derivative; 4-Deoxy-3,4-[2-[(2-methylpropyl)amino]-2-oxoethylidene]rifamycin; Rifampicin intermediate; 4-O-[2-(Isobutylamino)-2-oxoethyl]rifamycin; 3-[[(2-Methylpropyl)amino]carbonyl]methyl]rifamycin S; Antibiotic X 5108; (12Z,14E,24E)-(2S,12S,14S,15R,16S,17R,18R,19R,20S,21S,22R,23S)-21-Acetoxy-15-[(2S,4S,5S,6S)-5-[(2S,3S,4R,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-8-yl 2-methylbut-2-enoate
EINECS	Contact for details

Quality Control

Our 4-o-[2-(Methylpropylamino)-2-Oxoethyl]Rifamycin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere for long-term stability. Keep the container tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Reddish-brown to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.