Description

2 3 4 5 6-Pentafluorobenzoic Anhydride is a highly fluorinated aromatic anhydride, serving as a critical building block for introducing the pentafluorophenyl group into target molecules. Its primary value lies in its exceptional reactivity as an acylating agent, enabling the synthesis of advanced intermediates with enhanced stability and unique physicochemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors, particularly for developing active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: Key reagent for synthesizing active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the pentafluorophenyl moiety imparts weather resistance and biological activity.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, enhancing thermal stability and optical properties.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, improving chemical resistance, lowering surface energy, and enhancing material performance.
• Derivatization Agent for Analytics: Used in analytical chemistry to derivative compounds for enhanced detection via GC-MS or LC-MS, particularly for sensitive assay development.
• Organic Synthesis Reagent: A versatile acylating and coupling agent in complex organic synthesis for academic research and process development in fine chemicals.

Basic Information

Item	Detail
Product Name	2 3 4 5 6-Pentafluorobenzoic Anhydride
CAS No.	15989-99-8
Molecular Formula	C14F10O3
Molecular Weight	406.13 g/mol
Synonyms	Pentafluorobenzoic Anhydride; Perfluorobenzoic Anhydride; 2,3,4,5,6-Pentafluorobenzoic Acid Anhydride; Benzoic Acid, 2,3,4,5,6-Pentafluoro-, Anhydride; Pentafluorobenzoyl Anhydride; PFBA; Pentafluorophenyl Anhydride; Pentafluorobenzoic Acid Anhydride
EINECS	Contact for details

Quality Control

Our 2 3 4 5 6-Pentafluorobenzoic Anhydride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and IR are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	89 - 93 °C
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.