Description

2-(2'-Carboxyphenyl)Benzoyl-6-Aminopenicillanic Acid is a key semi-synthetic penicillin derivative and a crucial advanced pharmaceutical intermediate. Its primary value lies in its role as a versatile building block for the synthesis of novel β-lactam antibiotics, enabling the development of compounds with enhanced efficacy and resistance profiles. This high-purity intermediate is essential for research institutions and manufacturers in the pharmaceutical and fine chemical sectors focused on antibiotic development and production.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of novel penicillin and cephalosporin-based antibiotics.
• Antibiotic Research & Development: Serves as a core scaffold for medicinal chemists to develop new β-lactam compounds with targeted activity against resistant bacterial strains.
• Fine Chemical Synthesis: Used in the production of specialized chemical entities for biological testing and structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in controlled synthesis processes for producing specific antibiotic APIs under GMP conditions.

Basic Information

Product Name	2-(2'-Carboxyphenyl)Benzoyl-6-Aminopenicillanic Acid
CAS No.	14796-35-1
Molecular Formula	C22H20N2O6S
Molecular Weight	440.47 g/mol
Synonyms	6-APA, 2-(2'-Carboxybenzoyl) Derivative; 2-Carboxybenzoyl-6-aminopenicillanic Acid; 6-Aminopenicillanic Acid, 2-(2'-carboxybenzoyl)-; 2-(2-Carboxyphenyl)benzoyl-6-APA; (2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 2-(2-carboxybenzoyl)-; Penicillanic Acid Derivative; β-Lactam Intermediate
EINECS	Contact for details

Quality Control

Our 2-(2'-Carboxyphenyl)Benzoyl-6-Aminopenicillanic Acid is produced and tested to meet stringent quality standards suitable for pharmaceutical R&D and manufacturing. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.