Description

Mefruside Lactone is a key pharmaceutical intermediate and chemical building block. This compound is valued for its specific lactone structure, which is integral to the synthesis of more complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for development and production processes. Consistent quality and reliable supply are critical for its downstream applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of diuretic and antihypertensive agents.
• Organic Synthesis Building Block: Used in research and production of complex organic molecules, particularly those containing fused ring systems.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in pharmaceutical laboratories.
• Metabolite Studies: Employed in pharmacological and metabolic pathway research related to sulfonamide-derived drugs.
• Process Chemistry: Utilized in route scouting and optimization for the scalable manufacture of target compounds.

Basic Information

Product Name	Mefruside Lactone
CAS No.	14599-36-1
Molecular Formula	C12H14ClNO3S
Molecular Weight	287.76 g/mol
Synonyms	4-Chloro-N-methyl-3-(tetrahydro-2-oxo-3-furanyl)-2-benzothiazolesulfonamide; 3,4-Dihydro-2-methyl-4-oxo-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide lactone; Mefruside impurity C; Mefruside Lactone; 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-2-methyl-4-oxo-, 1,1-dioxide, lactone; Furosemide lactone analog
EINECS	Contact for details

Quality Control

Our Mefruside Lactone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR) and purity determination by HPLC, to ensure it meets exacting standards for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.