Description

Co-(Carboxymethyl)Cobalamin is a chemically modified derivative of Vitamin B12, where a carboxymethyl group is coordinated to the central cobalt ion. This structural modification enhances its stability and alters its biochemical properties, making it a valuable intermediate for advanced pharmaceutical synthesis and research. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and fine chemical industries for developing novel therapeutic agents and high-purity reference standards.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel cobalamin-based drugs and targeted therapies.
• Biochemical Research: Used as a stable, modified cofactor in enzymatic studies and metabolic pathway investigations.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical labs.
• Nutraceutical Development: Employed in the research and formulation of advanced, bioavailable vitamin B12 supplements.
• Diagnostic Reagents: A component in the development of diagnostic kits and assays for vitamin B12 deficiency.
• Catalyst Research: Investigated for its potential in asymmetric synthesis and green chemistry applications as an organocobalt catalyst.

Basic Information

Product Name	Co-(Carboxymethyl)Cobalamin
CAS No.	14517-61-4
Molecular Formula	C63H91CoN13O15P
Molecular Weight	Approx. 1400.3 g/mol
Synonyms	Carboxymethylcobalamin; Vitamin B12a Carboxymethyl Derivative; Coα-[α-(Carboxymethyl)]-Coβ-cyanocobamide; Cobinamide, Co-(carboxymethyl)-, cyanide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole; Co-(Carboxymethyl)-cyanocobalamin; Cobalamin, Co-(carboxymethyl)-
EINECS	Contact for details

Quality Control

Our Co-(Carboxymethyl)Cobalamin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and UV-Vis spectroscopy, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	Dark red crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (UV-Vis)	Characteristic absorption maxima
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.