Description

n-ε-2,4-Dnp-L-Lysine Hydrochloride is a chemically modified derivative of the essential amino acid L-lysine, specifically labeled with a 2,4-dinitrophenyl (DNP) group at the ε-amino position. This compound is a critical reagent and reference standard in biochemical and proteomic research, enabling the precise study of protein structure, function, and post-translational modifications. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and diagnostic manufacturers for applications in amino acid analysis, enzyme kinetics, and the development of analytical assays.

Application

• Biochemical Research Standard: Serves as a high-purity reference compound for calibrating analytical instruments like HPLC and mass spectrometers in amino acid analysis.
• Proteomics & Protein Chemistry: Used as a derivatization agent or model compound in studies of protein lysine modification, peptide mapping, and structural elucidation.
• Enzymology Studies: Acts as a substrate or inhibitor analog in kinetic assays to investigate the activity and specificity of enzymes such as transglutaminases or lysine-specific demethylases.
• Diagnostic Kit Development: Employed in the formulation and quality control of diagnostic reagents and kits for detecting specific amino acid metabolites or enzymatic activities.
• Pharmaceutical R&D: Utilized in drug discovery research for studying drug-protein interactions and the biochemical pathways involving modified amino acids.
• Academic Research & Teaching: Provides a well-defined, stable compound for advanced laboratory courses and fundamental research in biochemistry and molecular biology.

Basic Information

Product Name	n-ε-2,4-Dnp-L-Lysine Hydrochloride
CAS No.	14401-10-6
Molecular Formula	C12H17N5O6 • HCl
Molecular Weight	379.76 g/mol
Synonyms	Nε-(2,4-Dinitrophenyl)-L-lysine hydrochloride; N6-(2,4-Dinitrophenyl)-L-lysine hydrochloride; L-Lysine, N6-(2,4-dinitrophenyl)-, hydrochloride; DNP-L-lysine HCl; ε-DNP-L-lysine hydrochloride; 2,4-DNP-L-lysine hydrochloride; (S)-2-Amino-6-((2,4-dinitrophenyl)amino)hexanoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our n-ε-2,4-Dnp-L-Lysine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.