Description

4-(Trifluoromethyl)Bicyclo[2.2.2]Octane-1-Carboxylic Acid is a high-value, structurally complex fluorinated organic building block. This compound matters for its unique combination of a rigid bicyclic framework and a trifluoromethyl group, offering significant potential to modulate the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry, as a precursor for advanced materials, and in the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing rigid, lipophilic motifs.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides where the fluorinated bicyclic structure can enhance biological activity and environmental persistence.
• Advanced Material Precursor: Acts as a building block for specialty polymers, liquid crystals, or organic electronic materials requiring specific steric and electronic properties.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical space and improve drug-like properties.
• Fluorine Chemistry Reagent: Utilized in academic and industrial laboratories for methodological development in organofluorine chemistry.
• Ligand and Catalyst Development: Potential use in designing novel chiral ligands or catalysts due to its three-dimensional, sterically demanding structure.

Basic Information

Product Name	4-(Trifluoromethyl)Bicyclo[2.2.2]Octane-1-Carboxylic Acid
CAS No.	14234-09-4
Molecular Formula	C10H11F3O2
Molecular Weight	220.19 g/mol
Synonyms	4-(Trifluoromethyl)bicyclo[2.2.2]octane-1-carboxylic acid; 1-Carboxy-4-(trifluoromethyl)bicyclo[2.2.2]octane; Bicyclo[2.2.2]octane-1-carboxylic acid, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)bicyclo[2.2.2]octane-1-carboxylic acid; 4-Trifluoromethylbicyclo[2.2.2]octane-1-carboxylic acid; 4-(Trifluoromethyl)-1-bicyclo[2.2.2]octanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Bicyclo[2.2.2]Octane-1-Carboxylic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.