Description

Methyl 2,6-Difluorobenzoate is a high-purity fluorinated aromatic ester serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This intermediate is essential for research chemists and process development scientists in fine chemical, pharmaceutical, and crop protection industries seeking to introduce difluorobenzene motifs into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing difluorophenyl groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the difluoro substitution pattern can improve efficacy and selectivity.
• Liquid Crystal & Electronic Chemicals: Serves as a starting material for fluorinated liquid crystal compounds and other specialty electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions to create complex aromatic systems.
• Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in academic and industrial laboratories.
• Dye & Pigment Intermediate: Can be used in the synthesis of specialized fluorinated dyes and functional pigments.

Basic Information

Product Name	Methyl 2,6-Difluorobenzoate
CAS No.	13671-00-6
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	2,6-Difluorobenzoic Acid Methyl Ester; Methyl 2,6-Difluorobenzoate; Benzoic acid, 2,6-difluoro-, methyl ester; Methyl 2,6-Difluorobenzenecarboxylate; 2,6-Difluorophenyl Methyl Ester; Methyl o,o'-Difluorobenzoate; Methyl 2,6-Difluoro Benzoate
EINECS	Contact for details

Quality Control

Our Methyl 2,6-Difluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for use in regulated synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.