Description

Benzoyl Fluoride, 2,6-Difluoro- (8Ci,9Ci) CAS NO 13656-41-2 is a highly reactive and versatile fluorinated aromatic building block, essential for introducing the benzoyl fluoride moiety into complex molecular architectures. Its primary value lies in its role as a key intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) that require specific fluorine substitution patterns. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the difluorobenzoyl group imparts improved biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, enhancing thermal stability and optical properties.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, improving chemical resistance, surface properties, and durability.
• Cross-Coupling Reactions: Acts as an electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for constructing complex biaryl systems.
• Fluorination Reagent Precursor: Can be utilized to generate other fluorinating agents or to transfer the benzoyl fluoride functional group in synthetic sequences.

Basic Information

Product Name	Benzoyl Fluoride, 2,6-Difluoro- (8Ci,9Ci)
CAS No.	13656-41-2
Molecular Formula	C7H3F3O
Molecular Weight	160.10 g/mol
Synonyms	2,6-Difluorobenzoyl Fluoride; 2,6-Difluorobenzoic Acid Fluoride; Benzoyl Fluoride, 2,6-Difluoro-; 2,6-Difluorobenzoyl Fluoride (8CI,9CI); 2,6-Difluorobenzofluoride; α,α,2,6-Tetrafluorotoluene (obsolete); 2,6-Difluorophenylcarbonyl Fluoride
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluorobenzoyl Fluoride is manufactured and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring consistency and reliability for your critical synthesis workflows. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and strong acid/organic solvent nature, store in a cool (15-25°C), dry, and well-ventilated area, away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents. Use appropriate corrosion-resistant storage equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.