Description

Capreomycin is a cyclic peptide antibiotic complex produced by *Streptomyces capreolus*, primarily composed of Capreomycin IA and IB. This compound is a critical second-line therapeutic agent in the global fight against multidrug-resistant tuberculosis (MDR-TB). It is essential for pharmaceutical manufacturers, research institutions, and clinical laboratories developing and producing specialized anti-tuberculosis treatments.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of injectable second-line anti-tuberculosis drugs.
• Multidrug-Resistant Tuberculosis (MDR-TB) Treatment: A vital part of combination therapy regimens for patients resistant to first-line drugs like isoniazid and rifampin.
• Pharmaceutical Research & Development: Used in preclinical and clinical studies for developing new TB therapeutics and studying drug resistance mechanisms.
• Reference Standard: Serves as a high-purity standard in quality control laboratories for HPLC, LC-MS, and microbiological assay calibration.
• Microbiological Studies: Employed in research to investigate the efficacy, pharmacokinetics, and spectrum of activity of peptide antibiotics.

Basic Information

Product Name	Capreomycin
CAS No.	11003-38-6
Molecular Formula	C25H44N14O8 (Capreomycin IA)
Molecular Weight	668.71 g/mol (Capreomycin IA)
Synonyms	Capastat; Caprocin; Capromycin; Capreomycin Sulfate; Capreomycin IA; Capreomycin IB; D-Capreomycin; Cyclo[L-2,3-diaminopropionyl-D-lysyl-(4-amino-4-deoxy-α-D-glucopyranuronosyl)-(1→4)-D-serine]
EINECS	234-237-2

Quality Control

Our Capreomycin is manufactured and tested under strict quality management systems. We provide material compliant with pharmaceutical-grade standards, and comprehensive testing includes identification, potency (assay), impurity profile, and microbiological analysis. A detailed Certificate of Analysis (COA) is supplied with each batch, ensuring traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Composition (Capreomycin IA & IB)	Meets defined ratio
Water Content (KF)	≤ 10.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 2.5 EU/mg
Sterility (if required)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.