Description

2-(Trifluoromethoxy)Benzoic Acid is a high-value fluorinated aromatic building block characterized by its trifluoromethoxy (-OCF₃) substituent. This compound is essential for introducing lipophilicity, metabolic stability, and electron-withdrawing properties into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays (LCDs).
• Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique thermal, chemical, or surface properties.
• Organic Synthesis & Catalysis: Employed as a versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis.
• Material Science Research: Utilized in the development of organic semiconductors, photovoltaic materials, and other electronic chemicals.

Basic Information

Product Name	2-(Trifluoromethoxy)Benzoic Acid
CAS No.	1979-29-9
Molecular Formula	C₈H₅F₃O₃
Molecular Weight	206.12 g/mol
Synonyms	o-(Trifluoromethoxy)benzoic acid; 2-(Trifluoromethoxy)benzoic acid; Benzoic acid, 2-(trifluoromethoxy)-; α,α,α-Trifluoro-o-anisic acid; 2-Carboxy(trifluoromethoxy)benzene; o-Trifluoromethoxybenzoic acid; 2-TFMBA
EINECS	217-829-6

Quality Control

Our 2-(Trifluoromethoxy)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	96 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.