Description

Chlomethocillin CAS NO 1926-49-4 is a specialized penicillin-derived antibiotic intermediate of significant importance in modern pharmaceutical synthesis. Its primary value lies in its role as a crucial building block for the production of advanced β-lactam antibiotics, ensuring high-purity inputs for critical manufacturing processes. This compound is essential for pharmaceutical R&D laboratories, API (Active Pharmaceutical Ingredient) manufacturers, and fine chemical suppliers serving the global healthcare sector.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of semi-synthetic penicillin and cephalosporin antibiotics.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the production chain for formulating broad-spectrum antibacterial drugs.
• Research & Development: Employed in medicinal chemistry for developing new antibiotic analogs and studying structure-activity relationships (SAR).
• Fine Chemical Synthesis: Acts as a building block for creating complex molecules with β-lactam cores in contract manufacturing organizations (CMOs).
• Veterinary Medicine: Utilized in the development of antibacterial treatments for animal health.

Basic Information

Item	Details
Product Name	Chlomethocillin
CAS No.	1926-49-4
Molecular Formula	C19H21ClN2O5S
Molecular Weight	424.90 g/mol
Synonyms	6-[(Hexahydro-1H-azepin-1-yl)methyleneamino]penicillanic acid; 6-APA derivative; Clometocillin; Chlometocillin; Antibiotic 356 CT; Antibiotic CT 356; (2S,5R,6R)-6-[[(1-Azepanyl)methylideneamino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-[(Hexahydro-1H-azepin-1-yl)methyleneamino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
EINECS	217-677-6

Quality Control

Our Chlomethocillin is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for pharmaceutical applications. The product undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to meet the stringent requirements of API synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with each batch to support your quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.