Description

Ethyl 4-Fluorobenzoylformate is a versatile fluorinated aromatic ester, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the strategic introduction of both a fluorine atom and a reactive ketoester moiety, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), including potential kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated organic materials, such as liquid crystals and polymers, for electronic and optical applications.
• Chemical Biology Probes: Useful in designing fluorinated probes and tags for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	Ethyl 4-Fluorobenzoylformate
CAS No.	1813-94-1
Molecular Formula	C10H9FO3
Molecular Weight	196.18 g/mol
Synonyms	Ethyl 4-fluorobenzoylformate; Ethyl (4-fluorobenzoyl)formate; 4-Fluorobenzoylformic Acid Ethyl Ester; Ethyl α-oxo-4-fluorobenzeneacetate; Ethyl 2-oxo-2-(4-fluorophenyl)acetate; 4-Fluorophenylglyoxylic Acid Ethyl Ester; 1813-94-1; p-Fluorobenzoylformic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Fluorobenzoylformate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and industrial use. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.