Description

4-Chloro-3-(Trifluoromethyl)Benzoic Acid is a versatile fluorinated aromatic building block of significant industrial importance. Its unique structure, featuring both chloro and trifluoromethyl substituents, makes it a critical intermediate for synthesizing advanced molecules with tailored properties. This compound is essential for research and production in the pharmaceutical and agrochemical sectors, where it is used to create active ingredients with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of molecules targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Serves as a foundational component in manufacturing advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Liquid Crystal Materials: Used in the production of fluorinated liquid crystals for high-performance displays due to its ability to modify polarity and mesomorphic properties.
• Polymer Additives: Incorporated as a monomer or modifier to enhance the chemical resistance, thermal stability, and surface properties of specialty polymers.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki and Buchwald-Hartwig couplings, to introduce the chlorotrifluoromethylphenyl moiety into complex organic frameworks.
• Material Science Research: Utilized in R&D for creating novel organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethyl)Benzoic Acid
CAS No.	1737-36-6
Molecular Formula	C8H4ClF3O2
Molecular Weight	224.56 g/mol
Synonyms	4-Chloro-3-(trifluoromethyl)benzoic acid; 3-Trifluoromethyl-4-chlorobenzoic acid; Benzoic acid, 4-chloro-3-(trifluoromethyl)-; 4-Chloro-alpha,alpha,α-trifluoro-m-toluic acid; 4-Chloro-3-trifluoromethylbenzoic acid; 2-Chloro-5-carboxybenzotrifluoride; 4-Chloro-3-trifluoromethyl-benzoic acid; 4-Chloro-3-trifluoromethylbenzoic acid (CTFBA)
EINECS	217-083-5

Quality Control

Our production of 4-Chloro-3-(Trifluoromethyl)Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at ambient temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.