Description

(4-Fluoro-Phenyl)-Propynoic Acid Ethyl Ester is a versatile fluorinated organic building block characterized by its phenyl, propynoate, and fluorine functionalities. This compound matters as a key synthetic intermediate, enabling the efficient construction of complex molecules for advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and advanced material scientists for applications in medicinal chemistry, crop protection, and specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and inflammatory pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the fluorine atom for enhanced biological activity and environmental stability.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic frameworks with tailored properties.
• Chemical Biology Probes: Employed in the creation of fluorescent tags and molecular probes for studying biological processes due to its alkyne handle for click chemistry.
• Liquid Crystal & OLED Materials: Utilized as a building block for electronic materials, where its rigid, conjugated structure contributes to desired photophysical properties.

Basic Information

Product Name	(4-Fluoro-Phenyl)-Propynoic Acid Ethyl Ester
CAS No.	1736-31-8
Molecular Formula	C₁₁H₉FO₂
Molecular Weight	192.19 g/mol
Synonyms	Ethyl 3-(4-Fluorophenyl)propiolate; 4-Fluorophenylpropiolic Acid Ethyl Ester; Ethyl (4-Fluorophenyl)propynoate; 3-(4-Fluorophenyl)-2-propynoic Acid Ethyl Ester; p-Fluorophenylpropiolic Acid Ethyl Ester; Ethyl p-Fluorophenylpropiolate; 1736-31-8; FPPE
EINECS	217-082-5

Quality Control

Our (4-Fluoro-Phenyl)-Propynoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.