Description

6-Fluoro-2-Phenyl-4-Quinolinecarboxylic Acid is a high-value, fluorinated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and specific physicochemical properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a building block for creating organic semiconductors, fluorescent dyes, and metal-chelating ligands.
• Chemical Synthesis: A versatile fluorinated intermediate for introducing the quinoline core into more complex molecular architectures via cross-coupling and condensation reactions.
• Academic & R&D: Essential reference standard and starting material in medicinal chemistry and organic synthesis research within university and corporate laboratories.

Basic Information

Product Name	6-Fluoro-2-Phenyl-4-Quinolinecarboxylic Acid
CAS No.	1647-88-7
Molecular Formula	C₁₆H₁₀FNO₂
Molecular Weight	267.26 g/mol
Synonyms	6-Fluoro-2-phenylquinoline-4-carboxylic acid; 2-Phenyl-6-fluoro-4-quinolinecarboxylic acid; 4-Quinolinecarboxylic acid, 6-fluoro-2-phenyl-; 6-Fluoro-2-phenyl-4-quinolincarboxylic acid; 6-Fluoro-2-phenylcinchoninic acid; FQCA; 1647-88-7; 6-Fluoro-2-phenylquinoline-4-carboxylate
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2-Phenyl-4-Quinolinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.