Description

2-Bromo-5-(Trifluoromethyl)Benzoic Acid is a versatile and high-value aromatic building block characterized by its bromine and trifluoromethyl substituents. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers for advanced polymers, liquid crystals, and organic electronic materials due to its halogenated and fluorinated structure.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-5-(Trifluoromethyl)Benzoic Acid
CAS No.	1483-56-3
Molecular Formula	C8H4BrF3O2
Molecular Weight	269.02 g/mol
Synonyms	5-(Trifluoromethyl)-2-bromobenzoic Acid; 2-Bromo-α,α,α-trifluoro-m-toluic Acid; Benzoic acid, 2-bromo-5-(trifluoromethyl)-; 2-Bromo-5-trifluoromethylbenzoic Acid; 2-Bromo-α,α,α-trifluoro-m-toluic acid; m-Trifluoromethyl-2-bromobenzoic Acid; 2-Bromo-5-(trifluoromethyl)benzenecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-(Trifluoromethyl)Benzoic Acid is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, ensure the container is made of compatible materials and is properly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.