Description

(3S,5R,6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-Octadecahydro-17-(3-hydroxypropyl-13C3)-10,13-dimethyl-5H-dicyclopropa[6,7:15,16]cyclopenta[a]phenanthrene-3,5,17-triol is a high-purity, isotopically labeled steroidal compound, specifically a carbon-13 labeled derivative of a complex polycyclic alcohol. This compound is critical for advanced research and development, serving as a precise internal standard or tracer in analytical and metabolic studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in sophisticated pharmacokinetics, drug metabolism, and biomarker research.

Application

• Internal Standard for LC-MS/MS: Provides unparalleled accuracy in the quantitative bioanalysis of steroidal drugs and endogenous metabolites due to its isotopic label, minimizing matrix effects.
• Metabolic Pathway Tracing: Used in in vitro and in vivo studies to elucidate the absorption, distribution, metabolism, and excretion (ADME) profiles of novel therapeutic agents.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for method development, validation, and quality control in drug manufacturing under GMP guidelines.
• Biomarker Research: Enables sensitive and specific detection and quantification of steroidal biomarkers in complex biological matrices for diagnostic development.
• Stable Isotope Labeled Compound (SIL) Synthesis: Acts as a key intermediate or building block for synthesizing more complex isotopically labeled molecules for research.

Basic Information

Product Name	(3S,5R,6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-Octadecahydro-17-(3-hydroxypropyl-13C3)-10,13-dimethyl-5H-dicyclopropa[6,7:15,16]cyclopenta[a]phenanthrene-3,5,17-triol
CAS No.	1264137-83-8
Molecular Formula	C26H42O3 (with three carbon-13 atoms)
Molecular Weight	~402.6 g/mol (exact mass varies with isotopic enrichment)
Synonyms	17-(3-Hydroxypropyl-13C3)-10,13-dimethyl-2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17-hexadecahydro-1H-cyclopenta[a]phenanthrene-3,5,17-triol; 13C3-Labeled Steroidal Triol; Carbon-13 Labeled Dicyclopropacyclopentaphenanthrene Triol; Isotopic Internal Standard for Steroid Analysis; [13C3]-HPDPT; (3S,5R,6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-17-[(3-Hydroxypropyl-1,2,3-13C3)]-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-3,5,17-triol
EINECS	Contact for details

Quality Control

Every batch of this high-value compound is produced and analyzed under strict quality protocols to ensure identity, purity, and isotopic enrichment meet exacting research standards. Our quality system employs advanced analytical techniques including NMR, HPLC, and High-Resolution Mass Spectrometry (HRMS). A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing the chemical purity, isotopic purity (atom % 13C), and chromatographic profile. Production can be aligned with GMP principles for use as a reference standard upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions or under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % 13C)	≥ 99% (on labeled positions)
Chemical Purity (by HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.