Description

L-Valine, [1-14C]- is a carbon-14 labeled isotopologue of the essential branched-chain amino acid L-Valine, specifically labeled at the 1-carbon position. This product is a critical tool for metabolic pathway tracing, pharmacokinetic studies, and protein synthesis research, offering high specific activity and radiochemical purity. It is primarily utilized by researchers and scientists in the pharmaceutical, biotechnology, and agrochemical industries for advanced radiolabeling and tracer applications.

Application

• Metabolic Pathway Analysis: Tracing the incorporation and fate of valine in biological systems.
• Drug Metabolism and Pharmacokinetics (DMPK): Radiolabeled studies to determine the absorption, distribution, metabolism, and excretion (ADME) of novel pharmaceutical compounds.
• Protein Biosynthesis Research: Investigating the kinetics and mechanisms of protein synthesis and turnover in cell cultures and model organisms.
• Nutritional Studies: Examining the utilization and requirements of this essential amino acid in metabolic research.
• Biochemical Assay Development: Serving as a labeled substrate or standard in enzymatic and receptor-binding assays.
• Agricultural Chemical Research: Studying the metabolism and environmental fate of compounds in plants and soil.

Basic Information

Product Name	L-Valine, [1-14C]-
CAS No.	14330-62-2
Molecular Formula	C514CH11NO2
Molecular Weight	~118.16 g/mol (for unlabeled); Contact for specific activity details.
Synonyms	(2S)-2-Amino-3-methyl[1-14C]butanoic acid; L-(1-14C)Valine; L-α-Aminoisovaleric acid-1-14C; [1-14C]-L-Valine; Valine-1-14C; (S)-2-Amino-3-methyl[1-14C]butyric acid; L-Valine (carbon-14 labeled); Radiolabeled L-Valine
EINECS	Contact for details.

Quality Control

Every batch of L-Valine, [1-14C]- is manufactured and analyzed under strict quality systems to ensure radiochemical purity and specific activity meet the highest standards for research. Our products undergo rigorous quality testing, including HPLC and radio-HPLC analysis, to ensure compliance with stringent specifications. Certificates of Analysis (COA) detailing specific activity, radiochemical purity, chemical purity, and solvent composition are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C or as specified on the label or Certificate of Analysis. This product is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to minimize exposure to atmospheric moisture. For long-term storage, consider conditions recommended for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid or solution (as supplied)
Identification (IR / NMR)	Conforms to structure
Specific Activity	Contact for details (mCi/mmol)
Radiochemical Purity (HPLC)	≥ 97%
Chemical Purity (HPLC)	≥ 98%
Solvent (if supplied as solution)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.