Description

L-Phenylalanine, [14C(U)]- is a uniformly carbon-14 labeled isotopologue of the essential amino acid L-phenylalanine, identified by CAS number 14330-67-7. This radiolabeled compound is a critical tool for metabolic pathway tracing, pharmacokinetic studies, and protein synthesis research, offering unparalleled insight into biological systems. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in advanced biochemical and drug metabolism studies.

Application

• Tracer Studies in Metabolism Research: Used to investigate the metabolic fate, absorption, and distribution of phenylalanine and related compounds in vivo and in vitro.
• Drug Discovery & Development: Essential for conducting ADME (Absorption, Distribution, Metabolism, Excretion) studies of new pharmaceutical entities to understand their biotransformation pathways.
• Biochemical Pathway Analysis: Enables the elucidation of biosynthetic and catabolic pathways in microorganisms, plants, and animals.
• Protein Synthesis & Turnover Research: Incorporated into newly synthesized proteins to study protein dynamics, half-life, and turnover rates.
• Clinical Diagnostic Research: Applied in research related to metabolic disorders such as Phenylketonuria (PKU).
• Agricultural & Nutritional Science: Used in studies examining amino acid utilization and protein metabolism in livestock and crops.

Basic Information

Product Name	L-Phenylalanine, [14C(U)]-
CAS No.	14330-67-7
Molecular Formula	C9H1114CNO2 *
Molecular Weight	Contact for details
Synonyms	(S)-2-Amino-3-(phenyl-[U-14C])propanoic acid; L-14C-Phenylalanine; Uniformly Labeled 14C-L-Phenylalanine; Phenylalanine (L-isomer), [U-14C]-; L-α-Amino-β-phenyl[U-14C]propionic Acid; [U-14C]-L-Phe; F (U-14C)
EINECS	Contact for details

* Formula indicates uniform carbon-14 labeling across the phenyl ring.

Quality Control

Our radiolabeled compounds are produced and handled under strict quality systems to ensure high chemical, radiochemical, and isotopic purity. Each batch is analyzed to confirm identity, specific activity, and purity, with compliance to relevant guidelines for radioactive materials. Certificates of Analysis (COA) detailing chromatographic purity (HPLC), specific activity (mCi/mmol or GBq/mmol), and solvent composition are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage of solutions, consider aliquoting and storing under inert atmosphere to minimize radiolysis and decomposition. Handle and dispose of in accordance with all applicable local, national, and international radiation safety regulations.

Specification

Item	Specification
Appearance	White to off-white solid or solution (as specified)
Identification (HPLC/MS)	Conforms
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity (Radio-HPLC)	≥ 97%
Specific Activity	Customizable (e.g., 50-600 mCi/mmol)
Solvent (if supplied as solution)	Ethanol/Water or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.