Description

[1-14C] Acetyl is a carbon-14 radiolabeled derivative of the acetyl functional group, a critical building block in organic synthesis and metabolic studies. This compound is essential for researchers requiring precise isotopic tracing to elucidate biochemical pathways, reaction mechanisms, and pharmacokinetic profiles. It is primarily utilized by pharmaceutical R&D teams, agrochemical scientists, and academic institutions engaged in advanced tracer studies and analytical method development.

Application

• Tracer Studies in Drug Metabolism and Pharmacokinetics (DMPK): Used to label drug candidates for tracking absorption, distribution, metabolism, and excretion (ADME) in vivo.
• Biochemical Pathway Analysis: Employed to trace the incorporation of acetyl groups in critical processes like histone acetylation, fatty acid synthesis, and acetylcholine metabolism.
• Organic Synthesis Intermediate: Serves as a radiolabeled synthon for the preparation of more complex carbon-14 labeled compounds for research and regulatory submission packages.
• Environmental Fate Studies: Applied in agrochemical research to study the degradation, metabolism, and environmental fate of pesticides and herbicides.
• Analytical Reference Standard: Used as a certified standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and other analytical techniques for quantification and method validation.

Basic Information

Product Name	[1-14C] Acetyl
CAS No.	15762-07-9
Molecular Formula	C₂H₃¹⁴CO (commonly represented for the labeled moiety)
Molecular Weight	~45.05 g/mol (for unlabeled acetyl); specific activity provided per batch
Synonyms	Acetyl-1-14C; [1-14C]Acetyl group; 1-14C-Acetyl; Carbon-14 Labeled Acetyl; Radiolabeled Acetyl; CH₃¹⁴CO-; Ethanonyl-1-14C
EINECS	Contact for details

Quality Control

Every batch of [1-14C] Acetyl is manufactured and controlled under a strict quality management system. Product specifications, including radiochemical purity (typically >98% by HPLC) and specific activity, are rigorously verified. A comprehensive Certificate of Analysis (COA) detailing analytical results from techniques such as HPLC and LC-MS is supplied with each shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a designated, well-ventilated area for radioactive materials. Due to its highly volatile nature, ensure containers are securely sealed and handled in appropriate fume hoods to prevent loss and exposure.

Specification

Item	Specification
Appearance	Solution (specified solvent)
Identification (IR/NMR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 98%
Specific Activity	Batch-specific (mCi/mmol)
Chemical Purity (HPLC/GC)	≥ 95%
Solvent	As specified (e.g., Toluene, Benzene)
Concentration	Batch-specific (mCi/mL)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.