Description

N-[(11bR)-2,6-bis[3,5-bis(trifluoromethyl)phenyl]-8,9,10,11,12,13,14,15-octahydro-4-oxidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]-1,1,1-trifluoro-Methanesulfonamide is a sophisticated, chiral organophosphorus compound designed for high-performance applications in advanced chemical synthesis. This compound is valued for its role as a highly selective catalyst or ligand, particularly in asymmetric transformations critical to modern pharmaceutical and agrochemical development. It is essential for R&D chemists and process engineers in the fine chemical, pharmaceutical, and advanced materials sectors who require precise molecular control to develop novel active ingredients and functional molecules.

Application

• Asymmetric Catalysis: Serving as a key chiral ligand or catalyst precursor in enantioselective hydrogenation, cross-coupling, and C-H activation reactions.
• Pharmaceutical Intermediate Synthesis: Enabling the production of chiral active pharmaceutical ingredients (APIs) with high enantiomeric purity for therapeutic drugs.
• Agrochemical Research: Facilitating the development of novel, stereochemically defined pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Potential use in the synthesis of chiral polymers or advanced organic frameworks for electronic or optical applications.
• Process Chemistry Optimization: Implementation in scale-up and manufacturing processes to improve yield, selectivity, and cost-efficiency of complex molecules.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	N-[(11bR)-2,6-bis[3,5-bis(trifluoromethyl)phenyl]-8,9,10,11,12,13,14,15-octahydro-4-oxidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]-1,1,1-trifluoro-Methanesulfonamide
CAS No.	1261302-64-0
Molecular Formula	C41H24F15NO5PS
Molecular Weight	931.65 g/mol
Synonyms	(R)-DTBM-SEGPHOS Triflylamide; (11bR)-4-[(Trifluoromethyl)sulfonamido]-2,6-bis[3,5-bis(trifluoromethyl)phenyl]-4H,8H-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-Oxide; N-[(11bR)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]-8,9,10,11,12,13,14,15-octahydro-4-oxidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]-1,1,1-trifluoromethanesulfonamide; DTBM-SEGPHOS-TfN; Chiral Phosphine-Oxazoline Ligand Derivative; (R)-DTBM-SEGPHOS Trifluoromethanesulfonamide
EINECS	Contact for details

Quality Control

Every batch of our chiral organophosphorus compounds is produced and tested under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity, meeting the stringent requirements of catalysis and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and residual solvent content is provided with each shipment to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is sensitive to strong alkali and fluoride ions; ensure storage areas are separate from such materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.