Description

Bis(2,4,6-Trimethylphenyl)Phosphine is a sterically hindered tertiary phosphine ligand widely used in organometallic chemistry and catalysis. Its primary value lies in its ability to stabilize reactive metal centers and modulate catalytic activity in cross-coupling and hydrogenation reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-performance ligands for complex synthesis.

Application

• Catalyst Ligand in Cross-Coupling Reactions: A key component in Buchwald-Hartwig amination, Suzuki-Miyaura, and other palladium-catalyzed C-C and C-N bond-forming reactions for pharmaceutical intermediates.
• Hydrogenation & Hydrosilylation Catalysis: Used as a ligand for rhodium, iridium, and ruthenium complexes in asymmetric hydrogenation and hydrosilylation processes.
• Polymerization Initiator/Co-catalyst: Employed in the synthesis of specialized polymers and materials, including olefin polymerization and ring-opening metathesis polymerization (ROMP).
• Organic Synthesis Reagent: Acts as a reducing agent or nucleophilic catalyst in various fine chemical and academic research applications.
• Material Science & OLED Development: Utilized in the preparation of phosphorescent complexes for organic light-emitting diodes (OLEDs) and other electronic materials.

Basic Information

Product Name	Bis(2,4,6-Trimethylphenyl)Phosphine
CAS No.	1732-66-7
Molecular Formula	C24H27P
Molecular Weight	346.44 g/mol
Synonyms	Tri(2,4,6-Trimethylphenyl)Phosphine (common misnomer); Tris(mesityl)phosphine; Mes3P; Tris(2,4,6-trimethylphenyl)phosphine; Phosphinidene, tris(2,4,6-trimethylphenyl)-; 2,4,6-Trimethylphenylphosphine; Tris(mesityl)phosphane
EINECS	217-069-8

Quality Control

Our Bis(2,4,6-Trimethylphenyl)Phosphine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding catalytic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our global customer base in research and production.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and moisture-sensitive; containers should be purged with inert gas after each opening to maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.