Description

Tris(Pentafluorophenyl)Phosphine is a highly fluorinated organophosphorus compound prized for its exceptional electron-withdrawing properties and air-stable nature. This makes it a superior ligand in transition metal catalysis, particularly for cross-coupling reactions like Suzuki-Miyaura and Buchwald-Hartwig aminations, where it enhances catalyst activity and stability. It is a critical reagent for researchers and manufacturers in pharmaceutical development, advanced material science, and the synthesis of specialty chemicals who require reliable, high-performance catalytic systems.

Application

• As a highly effective ligand in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Negishi, Buchwald-Hartwig).
• Catalyst component in the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• Precursor for the preparation of other specialized phosphine ligands and organometallic complexes.
• Used in materials science for the synthesis of organic electronic materials and polymers.
• Facilitates hydrofunctionalization reactions (e.g., hydrosilylation, hydroboration).
• Employed in academic and industrial R&D for developing new catalytic methodologies.

Basic Information

Product Name	Tris(Pentafluorophenyl)Phosphine
CAS No.	1259-35-4
Molecular Formula	C18F15P
Molecular Weight	532.13 g/mol
Synonyms	Tris(2,3,4,5,6-Pentafluorophenyl)Phosphine; P(C6F5)3; Tris(pentafluorophenyl)phosphane; Tris(perfluorophenyl)phosphine; P(ArF)3; TPPF; 2,3,4,5,6-Pentafluorophenylphosphine trimer
EINECS	215-019-6

Quality Control

Our Tris(Pentafluorophenyl)Phosphine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed under an inert atmosphere to maintain product integrity over extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
31P NMR	Conforms
Melting Point	115 - 120 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.