Description

Diphenyl(p-Tolyl)Phosphine is a versatile organophosphorus compound widely used as a key ligand in transition metal catalysis. Its primary value lies in facilitating critical cross-coupling and other organometallic reactions essential for modern chemical synthesis. This product is particularly important for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate Synthesis: Acts as a crucial ligand in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) for constructing complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Production: Used in the synthesis of advanced pesticides and herbicides, where its role in catalysis enables the creation of specific, bioactive chemical structures.
• Material Science Research: Serves as a precursor or ligand in the development of novel organometallic complexes, polymers, and functional materials with tailored properties.
• Fine Chemical Manufacturing: Employed in the production of specialty chemicals, dyes, and pigments where precise catalytic control is required.
• Academic & Industrial R&D: A fundamental reagent for exploring new catalytic methodologies and reaction pathways in both laboratory and pilot-scale settings.
• Ligand for Homogeneous Catalysis: Its electron-donating properties make it effective in various homogeneous catalytic cycles beyond cross-coupling, including hydrogenation and hydroformylation.

Basic Information

Item	Details
Product Name	Diphenyl(p-Tolyl)Phosphine
CAS No.	1031-93-2
Molecular Formula	C19H17P
Molecular Weight	276.31 g/mol
Synonyms	p-Tolyldiphenylphosphine; (4-Methylphenyl)diphenylphosphine; Diphenyl(4-methylphenyl)phosphine; Phosphine, diphenyl(p-tolyl)-; Diphenyl-p-tolylphosphine; 4-Methyldiphenylphosphine; (p-Tolyl)diphenylphosphine; TPP (context-specific)
EINECS	213-852-6

Quality Control

Our Diphenyl(p-Tolyl)Phosphine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and 1H/31P NMR analysis, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. The container should be kept tightly sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	56 - 60 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.