Description

Tetrakis(Triphenylphosphine)Palladium is a highly versatile and widely used organometallic catalyst, essential for facilitating key carbon-carbon and carbon-heteroatom bond-forming reactions. Its primary value lies in its exceptional efficacy and selectivity in cross-coupling chemistry, enabling the efficient synthesis of complex organic molecules. This catalyst is a critical material for research and development laboratories, as well as production facilities, in the pharmaceutical, agrochemical, and advanced materials industries.

Application

This catalyst is indispensable in modern synthetic chemistry, with its primary applications including:

• Suzuki-Miyaura Cross-Coupling: For the synthesis of biaryl compounds, a common scaffold in pharmaceuticals and organic electronics.
• Heck Reaction: For the formation of carbon-carbon double bonds (alkenes) through the coupling of alkenes with aryl or vinyl halides.
• Sonogashira Coupling: For the synthesis of internal alkynes by coupling terminal alkynes with aryl or vinyl halides.
• Buchwald-Hartwig Amination: For the formation of carbon-nitrogen bonds to create aryl amines, a crucial transformation in drug discovery.
• Negishi Coupling: For the coupling of organozinc compounds with organic halides.
• Catalyst Precursor: Serves as a reliable source of palladium(0) for generating other active catalytic species in situ.
• Fine Chemical Synthesis: Used in the production of complex intermediates for active pharmaceutical ingredients (APIs), liquid crystals, and ligands.
• Academic & Industrial R&D: A staple reagent for methodological development and exploratory synthesis in chemistry laboratories worldwide.

Basic Information

Product Name	Tetrakis(Triphenylphosphine)Palladium
CAS No.	14221-01-3
Molecular Formula	C72H60P4Pd
Molecular Weight	1155.56 g/mol
Synonyms	Palladium(0) tetrakis(triphenylphosphine); Tetrakis(triphenylphosphine)palladium(0); Palladium-tetrakis(triphenylphosphine); Pd(PPh3)4; TPP Palladium; Pd(0) Catalyst; Tris(dibenzylideneacetone)dipalladium(0) alternative; Palladium tetrakis(triphenyl phosphine)
EINECS	238-086-9

Quality Control

Our Tetrakis(Triphenylphosphine)Palladium is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic activity. Each lot undergoes comprehensive analytical testing, including assay by titration and identification by spectroscopic methods. A Certificate of Analysis (COA) detailing purity, physical characteristics, and performance data is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to prevent oxidation and decomposition. The material is light-sensitive and easily oxidized; prolonged exposure to air, moisture, or ambient light will reduce catalytic activity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (Pd content)	≥ 9.0 % (by titration)
Purity (HPLC)	≥ 97.0 %
Solubility	Soluble in benzene, toluene, THF; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.