Description

S-(-)-1,1'-Binaphthyl-2,2'-Diol (CAS NO 1853-99-2) is a high-value, enantiomerically pure chiral compound widely recognized as (S)-BINOL. This compound is an essential chiral ligand and building block in asymmetric synthesis, enabling the production of pharmaceuticals and fine chemicals with high optical purity. It is critically needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel catalysts and chiral auxiliaries.

Application

• Asymmetric Catalysis: As a privileged chiral ligand for metal-catalyzed reactions, including hydrogenation, Diels-Alder, and aldol reactions.
• Pharmaceutical Intermediates: Key starting material for synthesizing enantiomerically pure active pharmaceutical ingredients (APIs).
• Chiral Resolution: Used to resolve racemic mixtures of alcohols, amines, and other compounds.
• Material Science: Building block for chiral polymers, liquid crystals, and molecular recognition systems.
• Agrochemical Synthesis: Production of chiral herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: Fundamental research tool in organic chemistry and process development.

Basic Information

Product Name	S-(-)-1,1'-Binaphthyl-2,2'-Diol
CAS No.	1853-99-2
Molecular Formula	C₂₀H₁₄O₂
Molecular Weight	286.32 g/mol
Synonyms	(S)-(-)-1,1'-Bi-2-naphthol; (S)-BINOL; (S)-(-)-BINOL; (S)-1,1'-Bi-2-naphthol; (S)-2,2'-Dihydroxy-1,1'-binaphthyl; (S)-1,1'-Binaphthalene-2,2'-diol; (S)-(-)-1,1'-Binaphthyl-2,2'-diol; Levo-1,1'-Bi-2-naphthol
EINECS	217-447-3

Quality Control

Our S-(-)-1,1'-Binaphthyl-2,2'-Diol is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity. All products undergo rigorous analytical testing, including HPLC, chiral analysis, and spectroscopic identification. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess (ee), and physical properties is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Melting Point	205 - 210 °C
Specific Rotation [α]²⁰D	-34.0° to -38.0° (c=1, THF)
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.