Description

9,9-Dimethyl-4,5-Bis(Diphenylphosphino)Xanthene is a high-value, air-stable bidentate phosphine ligand widely recognized for its electron-rich and sterically demanding properties. Its primary value lies in enabling highly efficient and selective transition metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig amination. This ligand is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require robust catalytic systems for synthesizing complex organic molecules.

Application

• Catalyst Ligand for Cross-Coupling Reactions: A key component in palladium-catalyzed Suzuki, Negishi, and Buchwald-Hartwig reactions for C-C and C-N bond formation.
• Pharmaceutical Intermediate Synthesis: Used in the development and scale-up of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Research: Facilitates the synthesis of novel herbicides, fungicides, and insecticides requiring selective coupling steps.
• Material Science & OLED Development: Employed in the synthesis of conjugated polymers and organic light-emitting diode (OLED) materials.
• Asymmetric Catalysis: Serves as a chiral ligand precursor or modifier in enantioselective hydrogenation and other asymmetric transformations.
• Academic & Industrial R&D: A staple reagent in research laboratories for methodological development and exploring new catalytic pathways.

Basic Information

Product Name	9,9-Dimethyl-4,5-Bis(Diphenylphosphino)Xanthene
CAS No.	1265-03-8
Molecular Formula	C39H32P2
Molecular Weight	562.62 g/mol
Synonyms	Xantphos; 4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene; 9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene; XantPhos Ligand; DPEphos analogue; Xantphos Pd G3 Precursor Ligand
EINECS	215-028-0

Quality Control

Our 9,9-Dimethyl-4,5-Bis(Diphenylphosphino)Xanthene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for catalytic applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at room temperature (15-25°C). This material is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided to maintain efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	215 - 220 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.