Description

Bis(3,5-Dimethylphenyl)Diethylaminophosphine is a specialized organophosphorus compound featuring a sterically hindered diethylaminophosphine group flanked by two 3,5-dimethylphenyl substituents. This molecular architecture makes it a highly effective and selective ligand in transition metal-catalyzed cross-coupling reactions, crucial for constructing complex organic frameworks. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for applications requiring precise stereochemical control and high catalytic activity.

Application

• As a ligand in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Buchwald-Hartwig aminations, for the synthesis of pharmaceuticals and agrochemicals.
• In the development of specialized catalysts for asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• For academic and industrial research in organometallic chemistry and new catalytic system design.
• As a precursor or intermediate in the synthesis of more complex phosphine ligands and functional materials.
• Potential use in material science applications, including the surface modification of nanoparticles and the creation of metal-organic frameworks (MOFs).

Basic Information

Product Name	Bis(3,5-Dimethylphenyl)Diethylaminophosphine
CAS No.	1636-15-3
Molecular Formula	C20H28NP
Molecular Weight	313.42 g/mol
Synonyms	Diethylamino-bis(3,5-dimethylphenyl)phosphine; (Diethylamino)bis(3,5-dimethylphenyl)phosphine; Diethyl(3,5-xylyl)phosphine; Phosphine, [bis(3,5-dimethylphenyl)]diethylamino-; Diethylaminobis(3,5-dimethylphenyl)phosphane
EINECS	Contact for details

Quality Control

Our production of Bis(3,5-Dimethylphenyl)Diethylaminophosphine adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity, which is critical for catalytic performance. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at room temperature (15-25°C) in a cool, dry, well-ventilated area. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
31P NMR	Conforms to structure
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.