Description

1,5-Cyclooctadiene{(4S)-(-)-2-[(5R)-6-(diphenylphosphino)spiro[4.4]nona-1.6-dien-1-yl]-4,5-dihydro-4-benzyloxazole}iridiuM(I) tetrakis[3,5-bis(trifluoroMethyl)phenyl]borate, 97% (R.S)-(COD)Ir[Bn-Spin is a high-purity, chiral iridium-based organometallic complex designed for advanced catalytic applications. This compound matters for its role as a highly selective and efficient catalyst in asymmetric synthesis, enabling the production of enantiomerically pure intermediates critical for pharmaceuticals and fine chemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control.

Application

• Asymmetric Hydrogenation: A key catalyst for the enantioselective reduction of prochiral olefins, imines, and ketones to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Enables the efficient and scalable production of single-enantiomer active pharmaceutical ingredients (APIs) and key chiral building blocks.
• Fine Chemical Manufacturing: Used in the synthesis of complex, high-value molecules for agrochemicals, flavors, and fragrances where stereochemistry is crucial.
• Methodology Development in Organic Chemistry: A valuable tool for academic and industrial research in developing new catalytic asymmetric transformations.
• Ligand Screening and Catalyst Optimization: Serves as a pre-formed catalyst for evaluating and optimizing reaction conditions in process chemistry.

Basic Information

Product Name	1,5-Cyclooctadiene{(4S)-(-)-2-[(5R)-6-(diphenylphosphino)spiro[4.4]nona-1.6-dien-1-yl]-4,5-dihydro-4-benzyloxazole}iridiuM(I) tetrakis[3,5-bis(trifluoroMethyl)phenyl]borate, 97% (R.S)-(COD)Ir[Bn-Spin
CAS No.	1195511-56-8
Molecular Formula	C71H56BF24IrNOP
Molecular Weight	~1572.9 g/mol
Synonyms	(R,S)-(COD)Ir[Bn-Spin] BArF; Iridium(I) (1,5-cyclooctadiene)[(4S)-(-)-2-[(5R)-6-(diphenylphosphino)spiro[4.4]nona-1,6-dien-1-yl]-4,5-dihydro-4-benzyloxazole] tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; (COD)Ir(SpiroBOP) BArF; Chiral Iridium-SpiroBOP Catalyst; Iridium Spiro Phosphino-Oxazoline Complex; Ir(SpiroBOP)(COD)BArF; Asymmetric Hydrogenation Catalyst (Iridium, SpiroBOP ligand); Contact for additional names.
EINECS	Contact for details

Quality Control

Our 97% grade product is manufactured under controlled conditions to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to confirm identity, purity, and the absence of deleterious impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (argon or nitrogen) due to its hygroscopic and light-sensitive nature. Keep away from strong bases and fluorides. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Iridium Content	Contact for details
Moisture Content (KF)	≤ 1.0%
Solubility	Soluble in dichloromethane, toluene, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.