Description

Vortioxetine Hydrobromide CAS NO 960203-27-4 is the hydrobromide salt form of vortioxetine, a modern multimodal antidepressant. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of finished pharmaceutical formulations. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of treatments for major depressive disorder (MDD).

Application

• Pharmaceutical API Manufacturing: Primary use as the active ingredient in the commercial production of antidepressant tablets and other dosage forms.
• Generic Drug Development: Serves as a key starting material for companies developing bioequivalent versions of branded vortioxetine medications.
• Clinical Research & Formulation Studies: Used in preclinical and clinical trials to study pharmacokinetics, dosage optimization, and new delivery systems.
• Reference Standard: High-purity grade suitable for use as a reference standard in analytical laboratories for quality control and method validation.
• Process Chemistry & Intermediate Synthesis: Employed in chemical synthesis for further molecular modifications or the creation of novel derivatives in research settings.

Basic Information

Item	Details
Product Name	Vortioxetine Hydrobromide
CAS No.	960203-27-4
Molecular Formula	C18H23BrN2O
Molecular Weight	379.29 g/mol
Synonyms	1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine hydrobromide; Vortioxetine HBr; Lu AA21004 hydrobromide; Brintellix (trade name) API; Trintellix (trade name) API; 5-HT3, 5-HT7, and 5-HT1D receptor antagonist; 5-HT1B receptor partial agonist; 5-HT1A receptor agonist; Serotonin reuptake inhibitor
EINECS	Contact for details

Quality Control

Our Vortioxetine Hydrobromide is manufactured under strict quality management systems. It undergoes rigorous analytical testing to meet pharmaceutical-grade specifications, including identity, purity, and impurity profile verification. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results against established criteria. Our quality commitment aligns with ICH guidelines and supports regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.