Description

5-[3-(Dimethylamino)-2-Methylpropyl]-5H-Dibenz[B,F]Azepine Hydrochloride is a high-purity pharmaceutical intermediate and active ingredient. This compound is critical for ensuring the quality and efficacy of downstream pharmaceutical formulations. It is primarily required by research institutions and manufacturers in the pharmaceutical and life sciences sectors for the development and production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex active pharmaceutical ingredients (APIs).
• Neurological Research: Used in preclinical and clinical research for studying neurological pathways and drug mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in laboratories.
• Active Pharmaceutical Ingredient (API): Direct incorporation into final dosage forms for therapeutic use.
• Chemical Synthesis: Utilized in organic synthesis for creating novel dibenzazepine derivatives with potential biological activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for GMP-grade production.

Basic Information

Product Name	5-[3-(Dimethylamino)-2-Methylpropyl]-5H-Dibenz[B,F]Azepine Hydrochloride
CAS No.	1159-80-4
Molecular Formula	C20H25ClN2
Molecular Weight	328.88 g/mol
Synonyms	Desipramine Hydrochloride; Desmethylimipramine Hydrochloride; Norimipramine Hydrochloride; Pertofrane; Nebril; Nortimil; Sertofren; 10,11-Dihydro-5-[3-(methylamino)propyl]-5H-dibenz[b,f]azepine Hydrochloride; 5-(3-Methylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine Hydrochloride
EINECS	214-579-7

Quality Control

Our 5-[3-(Dimethylamino)-2-Methylpropyl]-5H-Dibenz[B,F]Azepine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) documenting full compliance are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.