Description

Clorgyline Hydrochloride is a potent, selective, and irreversible inhibitor of monoamine oxidase A (MAO-A), a key enzyme in neurotransmitter metabolism. This high-purity compound is essential for advanced neuroscience research and pharmaceutical development, enabling precise studies on depression, anxiety, and neurodegenerative disorders. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and diagnostic manufacturers requiring reliable, well-characterized biochemical tools.

Application

• Neuroscience Research: As a selective MAO-A inhibitor for studying neurotransmitter dynamics, behavior, and neuropsychiatric conditions.
• Pharmaceutical R&D: A reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel antidepressant and neuroprotective agents.
• Biochemical Assay Development: Used to validate enzyme activity assays and high-throughput screening (HTS) platforms targeting monoamine oxidases.
• Academic Research: A critical tool in university and institutional labs for investigating the biochemical basis of mood disorders and Parkinson's disease.
• Diagnostic Manufacturing: A component in the production of diagnostic kits and reagents for neurological and metabolic testing.

Basic Information

Product Name	Clorgyline Hydrochloride
CAS No.	17780-75-5
Molecular Formula	C13H13ClN2 • HCl
Molecular Weight	273.17 g/mol
Synonyms	Clorgyline HCl; N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride; (3-(2,4-Dichlorophenoxy)-N-methyl-N-2-propynyl-1-propanamine hydrochloride); M&B 9302; Chlorgilin; Chlorgyline Hydrochloride; MAO-A Inhibitor I
EINECS	Contact for details

Quality Control

Our Clorgyline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.