Description

Setiptiline is a tricyclic compound with a unique tetracyclic structure, classified as a noradrenergic and specific serotonergic antidepressant (NaSSA). This compound matters for its role as a key pharmaceutical intermediate and reference standard in the research and development of novel central nervous system (CNS) agents. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions focused on neuropharmacology and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced antidepressant drug candidates.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) testing in pharmaceutical manufacturing.
• Biochemical Research: Employed in in vitro studies to investigate mechanisms of action related to norepinephrine and serotonin receptor systems.
• Medicinal Chemistry: A valuable compound for structure-activity relationship (SAR) studies aimed at developing new CNS-active therapeutics.
• Academic Research: Utilized in university and institutional labs for pharmacological and neurochemical research projects.

Basic Information

Product Name	Setiptiline
CAS No.	57262-94-9
Molecular Formula	C₂₀H₂₃N
Molecular Weight	277.41 g/mol
Synonyms	1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine; Org 8282; ORG-8282; Teciptiline; MO-8282; Setiptilin; Setiptylin
EINECS	Contact for details

Quality Control

Our Setiptiline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.