Description

Methyl 4-Formyl-2-(Trifluoromethyl)Benzoate CAS NO 959632-16-7 is a high-value trifluoromethylated aromatic building block, essential for introducing both aldehyde and ester functionalities into complex molecular architectures. Its primary value lies in enabling efficient synthetic routes to advanced intermediates for pharmaceuticals and agrochemicals, where the trifluoromethyl group is prized for its ability to modulate lipophilicity, metabolic stability, and bioavailability. This compound is critically needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Precursor: Employed in the synthesis of monomers and functionalized polymers for advanced materials with specific optical or electronic properties.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorinated Dye and Pigment Intermediate: Used in the production of specialty dyes and pigments where fluorine substitution alters light absorption and stability.

Basic Information

Product Name	Methyl 4-Formyl-2-(Trifluoromethyl)Benzoate
CAS No.	959632-16-7
Molecular Formula	C10H7F3O3
Molecular Weight	232.16 g/mol
Synonyms	Methyl 2-(Trifluoromethyl)-4-formylbenzoate; 4-Formyl-2-(trifluoromethyl)benzoic Acid Methyl Ester; 2-(Trifluoromethyl)terephthalaldehyde Methyl Ester; Benzoic acid, 4-formyl-2-(trifluoromethyl)-, methyl ester; Methyl 4-formyl-2-trifluoromethylbenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Formyl-2-(Trifluoromethyl)Benzoate adheres to stringent internal quality standards, ensuring batch-to-batch consistency for critical R&D and scale-up processes. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, IR) to confirm identity, purity, and impurity profile. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storage under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.