Description

(R)-Boc-4-Amino-6-Methylthio-Hexanoic Acid CAS NO 959582-93-5 is a high-purity, chiral building block featuring a protected amino group and a thioether side chain. This compound is critically important for the synthesis of complex, biologically active molecules where stereochemistry and specific functional group placement are essential. It is primarily needed by research and development teams in the pharmaceutical and biotechnology sectors for applications in drug discovery and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Peptidomimetic Synthesis: Used in the construction of peptide analogs and peptidomimetics, where the Boc-protected amino acid and methylthio moiety can be leveraged for further functionalization.
• Chemical Biology Probes: Serves as a building block for creating labeled compounds or probes used in studying biological pathways and target engagement.
• Ligand Development: Employed in the synthesis of specialized ligands for catalysis or as components in metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Research: A valuable starting material for custom synthesis houses and CROs (Contract Research Organizations) working on client-specific molecular targets.

Basic Information

Item	Detail
Product Name	(R)-Boc-4-Amino-6-Methylthio-Hexanoic Acid
CAS No.	959582-93-5
Molecular Formula	C₁₆H₃₁NO₄S
Molecular Weight	333.49 g/mol
Synonyms	(R)-6-((tert-Butoxycarbonyl)amino)-4-(methylthio)hexanoic acid; (R)-Boc-4-Amino-6-(methylthio)hexanoic Acid; (R)-N-Boc-4-Amino-6-methylmercaptohexanoic Acid; (R)-4-((tert-Butoxycarbonyl)amino)-6-(methylthio)hexanoic acid; (R)-Boc-Amino-Methylthio-Hexanoic Acid; (R)-Boc-NH-4-(SCH3)-C6 Acid; BOC-4-Amino-6-Methylthio-Hexanoic Acid (R-isomer)
EINECS	Contact for details

Quality Control

Our (R)-Boc-4-Amino-6-Methylthio-Hexanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.