Description

(2S,2′S)-1,1′-Bis(2-Pyridinylmethyl)-2,2′-Bipyrrolidine Tetrahydrochloride is a high-purity, chiral organic salt primarily utilized as a sophisticated ligand or catalyst precursor in asymmetric synthesis. Its value lies in enabling precise stereochemical control, which is critical for developing enantiomerically pure pharmaceutical intermediates and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for complex molecular construction.

Application

• Asymmetric Catalysis: Serving as a key chiral ligand or precursor for transition metal catalysts in enantioselective hydrogenation, cross-coupling, and C-H activation reactions.
• Pharmaceutical Intermediate Synthesis: Critical for the research and production of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for efficacy and environmental safety.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis within university laboratories and corporate R&D centers.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that demand high stereochemical purity.

Basic Information

Product Name	(2S,2′S)-1,1′-Bis(2-Pyridinylmethyl)-2,2′-Bipyrrolidine Tetrahydrochloride
CAS No.	959395-07-4
Molecular Formula	C22H30Cl4N4
Molecular Weight	500.31 g/mol
Synonyms	(S,S)-1,1'-Bis(2-pyridylmethyl)-2,2'-bipyrrolidine tetrahydrochloride; (2S,2'S)-1,1'-Bis(pyridin-2-ylmethyl)-[2,2'-bipyrrolidine]-1,1'-diium tetrachloride; (S,S)-Pyrrolidine Pyridine Ligand Tetrahydrochloride; Chiral Bipyridine Ligand Salt; (S,S)-BPPM Tetrahydrochloride; (2S,2'S)-BPyProl Tetrahydrochloride; (S,S)-Bis(2-pyridylmethyl)-2,2'-bipyrrolidine tetrahydrochloride
EINECS	Contact for details

Quality Control

Every batch of (2S,2′S)-1,1′-Bis(2-Pyridinylmethyl)-2,2′-Bipyrrolidine Tetrahydrochloride is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.