Description

7-(Trifluoromethyl)-1H-Indazole-3-Carboxylic Acid is a high-purity, versatile indazole derivative characterized by its trifluoromethyl functional group. This compound is a critical pharmaceutical intermediate and organic building block valued for its role in modulating the physicochemical properties of target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and oncology drug discovery programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of the indazole core.
• Material Science: Serves as a precursor for advanced organic frameworks, ligands for catalysis, and functional polymers.
• Chemical Biology: Employed as a probe or building block in the development of biochemical tools and diagnostic agents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis and scale-up projects.

Basic Information

Product Name	7-(Trifluoromethyl)-1H-Indazole-3-Carboxylic Acid
CAS No.	959236-70-5
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	1H-Indazole-3-carboxylic acid, 7-(trifluoromethyl)-; 7-(Trifluoromethyl)indazole-3-carboxylic acid; 7-Trifluoromethyl-1H-indazole-3-carboxylic acid; 959236-70-5; AI3-72085; ZINC000103014757; AKOS040759625; FT-0775787; EN300-1257525
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)-1H-Indazole-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.