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2-Bromo-6-Fluoro-3-Methylphenylboronic Acid CAS NO 957121-09-4


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CAS No.:957121-09-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Bromo-6-Fluoro-3-Methylphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing complex, fluorinated biaryl motifs.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with tailored properties.
  • Material Science: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
  • Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new catalytic processes and molecular architectures.
  • Suzuki-Miyaura Cross-Coupling: The primary application is as a boron-containing coupling partner with organic halides to form carbon-carbon bonds under palladium catalysis.
  • Ligand Synthesis: Can be utilized to create novel bidentate or polydentate ligands for metal catalysis.

Basic Information

Product Name 2-Bromo-6-Fluoro-3-Methylphenylboronic Acid
CAS No. 957121-09-4
Molecular Formula C7H7BBrFO2
Molecular Weight 231.85 g/mol
Synonyms (2-Bromo-6-fluoro-3-methylphenyl)boronic acid; 2-Bromo-6-fluoro-m-tolylboronic acid; B-(2-Bromo-6-fluoro-3-methylphenyl)boronic acid; 957121-09-4; Boronic acid, B-(2-bromo-6-fluoro-3-methylphenyl)-; 2-Fluoro-6-bromo-3-methylbenzeneboronic acid
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Quality Control

Our 2-Bromo-6-Fluoro-3-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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