Description

2-Tolylboronic Acid is a versatile organoboron compound, specifically an arylboronic acid derivative, that serves as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, a fundamental reaction for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active ingredients, functional polymers, and novel chemical entities.

Application

2-Tolylboronic Acid (CAS 16419-60-6) is a key reagent in cross-coupling reactions, facilitating the synthesis of a wide range of valuable compounds.

• Pharmaceutical Intermediates: Crucial for Suzuki-Miyaura cross-coupling reactions in the synthesis of drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Liquid Crystal & OLED Materials: Acts as a building block for constructing complex organic molecules used in display and lighting technologies.
• Polymer & Material Science: Incorporated into polymers to modify properties or create functional materials with specific electronic or mechanical characteristics.
• Chemical Research & Development: A standard reagent in academic and industrial R&D labs for methodological development and exploring new chemical spaces.
• Catalyst Ligand Precursor: Can be used to synthesize sophisticated ligands for transition metal catalysts.

Basic Information

Item	Details
Product Name	2-Tolylboronic Acid
CAS No.	16419-60-6
Molecular Formula	C7H9BO2
Molecular Weight	135.96 g/mol
Synonyms	o-Tolylboronic Acid; 2-Methylphenylboronic Acid; (2-Methylphenyl)boronic Acid; B-(2-Methylphenyl)boronic Acid; 2-Tolylboronic Acid; o-Toluene Boronic Acid; 2-Methylbenzeneboronic Acid; Boronic acid, B-(2-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 2-Tolylboronic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	~160-165 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.