Description

2,3-Difluorophenylboronic Acid is a high-purity organoboron compound, a key building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds. This reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require precise functionalization of aromatic systems to develop novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical synthon for constructing complex drug molecules, particularly in the development of active pharmaceutical ingredients (APIs) with difluorinated aromatic motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluorophenyl group enhances biological activity and stability.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom chemical synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	2,3-Difluorophenylboronic Acid
CAS No.	121219-16-7
Molecular Formula	C6H5BF2O2
Molecular Weight	157.92 g/mol
Synonyms	(2,3-Difluorophenyl)boronic Acid; 2,3-Difluorobenzeneboronic Acid; B-(2,3-Difluorophenyl)boronic Acid; 2,3-Difluorophenyl-Boric Acid; 121219-16-7; 2,3-Difluorophenylboronic acid (contains varying amounts of Anhydride)
EINECS	Contact for details

Quality Control

Our 2,3-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.