Description

3-(Trifluoromethyl)Phenylboronicacid is a high-value organoboron compound, specifically an arylboronic acid derivative, that serves as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl-substituted biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Employed in the production of organic light-emitting diodes (OLEDs), liquid crystals, and other advanced electronic materials requiring specific aryl-aryl linkages.
• Cross-Coupling Reactions: The quintessential reagent for Suzuki-Miyaura cross-coupling with various aryl halides, enabling carbon-carbon bond formation under mild conditions.
• Chemical Research & Development: A fundamental tool in medicinal chemistry and process chemistry for library synthesis and route scouting.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	3-(Trifluoromethyl)Phenylboronicacid
CAS No.	1423-26-6
Molecular Formula	C7H6BF3O2
Molecular Weight	189.93 g/mol
Synonyms	[3-(Trifluoromethyl)phenyl]boronic acid; m-Trifluoromethylphenylboronic acid; 3-Trifluoromethylbenzeneboronic acid; (3-Trifluoromethylphenyl)boronic acid; B-[3-(Trifluoromethyl)phenyl]boronic acid; 3-CF3-C6H4-B(OH)2; 3-Trifluoromethylphenylboronic Acid; 3-(Trifluoromethyl)benzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Phenylboronicacid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, NMR for structural confirmation, and Karl Fischer titration for moisture content. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and absorption of moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	~210-215 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.