Description

3-Tolylboronic Acid is a versatile organoboron compound, specifically a boronic acid derivative of toluene, widely used as a key building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, which is fundamental for constructing complex molecular architectures. This reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it facilitates the development of new active ingredients and functional compounds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A pivotal reagent for coupling with aryl halides to create biaryl structures, a common motif in drug discovery and material science.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of active pharmaceutical ingredients (APIs), particularly those containing substituted biphenyl or heterobiaryl units.
• Agrochemical Development: Serves as a building block for synthesizing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for transition metal catalysis and organometallic complexes.
• Material Science Research: Utilized in creating organic semiconductors, liquid crystals, and polymers with specific electronic or structural properties.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of molecular probes due to its selective reactivity with diols.

Basic Information

Product Name	3-Tolylboronic Acid
CAS No.	17933-03-8
Molecular Formula	C7H9BO2
Molecular Weight	135.96 g/mol
Synonyms	(3-Methylphenyl)boronic Acid; m-Tolylboronic Acid; 3-Methylbenzeneboronic Acid; B-(3-Methylphenyl)boronic Acid; m-Toluene Boronic Acid; 3-Tolylboronic Acid; 3-Methylphenylboronic Acid; m-Tolyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 3-Tolylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.