Description

(4-(Pentafluoro-L6-Sulfanyl)Phenyl)Boronic Acid is a specialized organoboron compound featuring a pentafluorosulfanyl (SF5) substituent, a highly electronegative and lipophilic group. This unique structure makes it a valuable building block in modern synthetic chemistry, particularly for creating novel materials and bioactive molecules with enhanced properties. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring the metabolically stable and strongly electron-withdrawing SF5 group to modulate bioavailability and potency.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides where the SF5 moiety can improve lipid membrane penetration and environmental stability.
• Materials Science: Serves as a monomer or functionalization agent in the creation of advanced polymers, liquid crystals, and electronic materials with unique dielectric or optical properties.
• Suzuki-Miyaura Cross-Coupling: Acts as a versatile boronic acid coupling partner for forming carbon-carbon bonds with aryl/vinyl halides, enabling the construction of complex biaryl structures common in drug discovery.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological systems, leveraging the distinctive spectroscopic signature of the SF5 group.

Basic Information

Product Name	(4-(Pentafluoro-L6-Sulfanyl)Phenyl)Boronic Acid
CAS No.	871507-70-9
Molecular Formula	C6H4BF5O2S
Molecular Weight	269.96 g/mol
Synonyms	4-(Pentafluoro-λ6-sulfanyl)benzeneboronic acid; 4-SF5-Phenylboronic Acid; [4-(Pentafluorosulfanyl)phenyl]boronic acid; (4-Pentafluorosulfanylphenyl)boronic acid; Boronic acid, B-[4-(pentafluoro-λ6-sulfanyl)phenyl]-; 871507-70-9; 4-(SF5)C6H4B(OH)2
EINECS	Contact for details

Quality Control

Every batch of (4-(Pentafluoro-L6-Sulfanyl)Phenyl)Boronic Acid undergoes rigorous analytical testing to ensure high purity and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development as well as scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its moisture-sensitive and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.