Description

4-Fluorobenzeneboronic Acid is a versatile organoboron compound widely used as a key building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, particularly in Suzuki-Miyaura cross-coupling reactions, which are fundamental to pharmaceutical and advanced material research. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing biaryl structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific fluorinated aromatic components.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Chemical Research & Development: A standard building block in academic and industrial R&D labs for constructing complex organic molecules and exploring new reaction methodologies.
• Fluorine Chemistry Studies: Used as a model substrate to study the influence of fluorine atoms on reaction kinetics and molecular properties.

Basic Information

Product Name	4-Fluorobenzeneboronic Acid
CAS No.	1765-93-1
Molecular Formula	C6H6BFO2
Molecular Weight	139.92 g/mol
Synonyms	(4-Fluorophenyl)boronic Acid; p-Fluorobenzeneboronic Acid; 4-Fluorophenylboronic Acid; B-(4-Fluorophenyl)boronic Acid; 4-Fluorophenyl-Boric Acid; 4-Fluorobenzeneboronic Acid (contains varying amounts of Anhydride); 4-Fluorophenylboronic Acid (contains varying amounts of Anhydride); 4-Fluorobenzene-1-boronic Acid
EINECS	217-195-4

Quality Control

Our 4-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	210 - 215 °C
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.